PT-141
Performance
PT-141 (Bremelanotide) is a synthetic melanocortin peptide studied for its activity at MC3 and MC4 receptor subtypes. Unlike peripheral vasodilators, PT-141 acts through the central nervous system, activating melanocortin pathways in the hypothalamus. It is a non-selective agonist at melanocortin receptors MC1R, MC3R, MC4R, and MC5R.
$44.95
In StockFor research purposes only. Not for human consumption.
Mechanism of Action
PT-141 is a non-selective agonist at melanocortin receptors MC1R, MC3R, MC4R, and MC5R. Unlike PDE5 inhibitors, it acts through the central nervous system rather than the vascular system, activating melanocortin pathways in the hypothalamus. Studies show it crosses the blood-brain barrier and activates dopaminergic neurons in the ventral tegmental area.
Research Focus Areas
- Melanocortin receptor signaling studies
- Neuroendocrine pathway modulation
- Central nervous system research
- Appetite and energy homeostasis models