Melanotan-2
Performance
Melanotan-2 (MT-2) is a synthetic analog of alpha-melanocyte-stimulating hormone (¦Á-MSH). It is a cyclic heptapeptide studied for its non-selective agonist activity at melanocortin receptors MC1R through MC5R. Research focuses on its role in melanogenesis, pigmentation pathways, and melanocortin-mediated signaling in preclinical models.
$45.00
In StockFor research purposes only. Not for human consumption.
Mechanism of Action
Melanotan-2 is a non-selective agonist at melanocortin receptors, primarily activating MC1R to stimulate eumelanin production in melanocytes via cAMP/PKA signaling. It also acts on MC3R and MC4R in the hypothalamus, influencing energy homeostasis and feeding behavior through central melanocortin pathway activation.
Research Focus Areas
- Melanocortin receptor signaling (MC1R–MC5R)
- Melanogenesis and pigmentation
- Photoprotection research models
- Appetite regulation via MC4R