Tesamorelin
Performance
Tesamorelin is a growth hormone-releasing hormone (GHRH) analog consisting of 44 amino acids. It binds to GHRH receptors on anterior pituitary somatotroph cells, stimulating the synthesis and pulsatile release of endogenous growth hormone. This triggers downstream IGF-1 production in hepatocytes via the JAK-STAT signaling pathway.
$35.00
In StockFor research purposes only. Not for human consumption.
Mechanism of Action
Tesamorelin binds to GHRH receptors on anterior pituitary somatotroph cells, stimulating the synthesis and pulsatile release of endogenous growth hormone. This triggers downstream IGF-1 production in hepatocytes via the JAK-STAT pathway. Clinical studies demonstrate it reduces visceral adipose tissue by 15-20% while preserving subcutaneous fat and lean body mass.
Research Focus Areas
- Growth hormone secretion pathways
- Lipodystrophy and fat metabolism
- IGF-1 signaling cascade studies
- Metabolic syndrome research models