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Sermorelin
Qty: 5mg / 1 BOTTLE
Purity: >99%
Mol: —
2-8°C
Metabolic

Sermorelin

Metabolic

Sermorelin (GHRH 1-29 NH2) is a synthetic analog of the first 29 amino acids of endogenous Growth Hormone-Releasing Hormone (GHRH). It acts on the pituitary gland to stimulate the natural, pulsatile secretion of growth hormone (GH). Unlike exogenous GH administration, Sermorelin works through the body's own regulatory feedback mechanisms, making it a widely studied compound in growth hormone axis research and age-related GH decline models.

$60.00

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For research purposes only. Not for human consumption.

Mechanism of Action

Sermorelin binds to the GHRH receptor (GHRHR) on anterior pituitary somatotroph cells, activating adenylyl cyclase and increasing intracellular cAMP, which triggers the synthesis and pulsatile release of growth hormone. Because it preserves the natural negative feedback loop via somatostatin, GH secretion remains physiologically regulated, distinguishing it from direct GH administration in research models.

Key Benefits

Pituitary GH axis research
GHRH receptor pathway studies
Growth hormone secretion models
Age-related decline research
Feedback loop preservation studies
Somatotroph function research