Selank
Performance
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) developed as a stable analogue of the endogenous immunomodulatory tetrapeptide tuftsin. Originally developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, Selank has been extensively studied for its anxiolytic and neuroprotective properties without sedative side effects. It is investigated in research models examining GABAergic modulation, BDNF expression support, serotonin and dopamine neurotransmitter pathway interactions, and cognitive enhancement through central nervous system signaling.
$55.00
In StockFor research purposes only. Not for human consumption.
Mechanism of Action
Selank modulates the GABAergic system by potentiating GABA-A receptor activity, producing anxiolytic effects without benzodiazepine-associated sedation or dependence in research models. It upregulates BDNF and NGF expression in hippocampal and cortical tissue, supporting neuroplasticity pathways. Selank also inhibits enkephalin-degrading enzymes, prolonging the activity of endogenous opioid peptides. Additionally, it has been studied for its immunomodulatory effects via tuftsin-like interactions with immune cell receptors, promoting interleukin balance in research models.
Research Focus Areas
- Anxiolytic activity without sedative effects research
- Cognitive enhancement and neuroplasticity studies
- BDNF and NGF upregulation pathway research
- GABAergic modulation research models