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Metabolic

GLP-3(Retatrutide)

Metabolic

Retatrutide (LY3437943) is a novel triple-agonist peptide that simultaneously targets GLP-1, GIP, and glucagon receptors. This triple mechanism produces synergistic metabolic effects beyond single or dual agonists. Phase 2 clinical trials have demonstrated significant results in metabolic research, making it one of the most studied multi-receptor agonists.

$55.00

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For research purposes only. Not for human consumption.

Mechanism of Action

Retatrutide simultaneously activates GLP-1R (enhancing insulin secretion), GIPR (potentiating incretin response), and GCGR (increasing energy expenditure and hepatic fat oxidation). This triple mechanism produces synergistic metabolic effects including enhanced glycemic control, increased thermogenesis, and improved hepatic lipid metabolism beyond what single or dual agonists achieve.

Key Benefits

Triple receptor agonism research
Metabolic pathway studies
Glycemic control models
Hepatic steatosis research
Incretin signaling studies
Energy expenditure research