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Skin & Repair

AHK-CU

Skin & Repair

AHK-Cu (Ala-His-Lys copper complex) is a copper-binding tripeptide closely related to GHK-Cu, with an alanine substitution at the N-terminus. It has been studied for its advanced copper peptide technology in skin biology research, with particular focus on collagen production support, skin rejuvenation pathways, and dermal repair mechanisms. AHK-Cu coordinates with copper(II) ions to form a stable complex that is investigated for its activity in extracellular matrix modeling and fibroblast signaling.

$35.00

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For research purposes only. Not for human consumption.

Mechanism of Action

AHK-Cu forms a coordination complex with copper(II) ions through N3O geometry, with the imidazole nitrogen of histidine serving as a primary metal-binding site. The copper complex modulates metalloproteinase activity and promotes collagen type I and III synthesis in dermal fibroblast research models. It has been studied for its role in activating TGF-β signaling pathways associated with ECM remodeling and tissue repair.

Key Benefits

Advanced copper peptide technology
Collagen synthesis pathway research
Skin rejuvenation model studies
ECM remodeling research
Dermal repair pathway studies
Fibroblast signaling research